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. 2020 Jul 14;20:655. doi: 10.1186/s12885-020-07123-6

Table 1.

Progression of the 12-month multi-modal exercise training program

Phase Cycle Weeks Session Type Frequency (per week) Duration/Dose Intensitya

Phase 1

Supervised Exercise During AC

1 1–3 Steady State & Resistance Training 2

SS: 30 mins

RT: 1–2 sets × 12–15 reps

SS: 10–20 b/min below %HRR at VT

RT: 60–70% 1RM

Interval Training 1 4 × 2 minsb %HRR at VT ± 5 b/min
2 4–6 Steady State & Resistance Training 2

SS: 30 mins

RT: 2 sets × 12–15 reps

SS: 10–15 b/min below %HRR at VT

RT: 60–70% 1RM

Interval Training 1 4 × 3 minsb %HRR at VT ± 5 b/min
3 7–9 Steady State & Resistance Training 2

SS: 30–35 min

RT: 2 sets × 18–12 reps

SS: 5–10 b/min below %HRR at VT

RT: 70–85% 1RM

Interval Training 1 4 × 3 minsb 85–95% HRpeak
4 10–12 Steady State & Resistance Training 2

SS: 35–40 min

RT: 2 sets × 8–12 reps

SS: 5–10 b/min below %HRR at VT

RT: 70–85% 1RM

Interval Training 1 4 × 4 minsb 85–95% HRpeak

Phase 2

Semi-supervised Exercise Following AC

1 13,15,17 Endurance Training 1 40–50 min 15–20 b/min below %HRR at VT
Tempo Training & Resistance Training 2

TT: 35 mins

RT: 2 sets × 8–12 reps

TT: 5–10 b/min below %HRR at VT

RT: 70–85% 1RM

Interval Training 1 4 × 4 minsb 85–95% HRpeak
14,16 Tempo Training 1 35 mins 5–10 b/min below %HRR at VT
Interval Training & Resistance Training 2

IT: 4 × 4 minsb

RT: 2 sets × 8–12 reps

IT: 85–95% HRpeak

RT: 70–85% 1RM

Recovery Session 1 30 mins 25–30 b/min below %HRR at VT
2 18,20,22 Tempo Training 1 35 mins 0–5 b/min below %HRR at VT
Interval Training & Resistance Training 2

IT: 4 × 4 minsb

RT: 2 sets × 8–12 reps

IT: 85–95% HRpeak

RT: 70–85% 1RM

Recovery Session 1 30 mins 20–25 b/min below %HRR at VT
19,21 Endurance Training 1 50–60 min 15–20 b/min below %HRR at VT
Tempo Training & Resistance Training 2

TT: 35 mins

RT: 2 sets × 8–12 reps

TT: %HRR at VT ± 5 b/min

RT: 2 sets × 8–12 reps

Interval Training 1 4 × 4 minsb 85–95% HRpeak
3 23,25 Endurance Training 1 60 mins 10–20 b/min below %HRR at VT
Tempo Training & Resistance Training 2

TT: 35 mins

RT: 2 sets × 8–12 reps

TT: %HRR at VT ± 10 b/min

RT: 70–85% 1RM

Interval Training 1 4 × 4 minsb 85–95% HRpeak
24,26 Tempo Training 1 35 mins %HRR at VT ± 10 b/min
Interval Training & Resistance Training 2

IT: 4 × 4 minsb

RT: 2 sets × 8–12 reps

IT: 85–95% HRpeak

RT: 70–85% 1RM

Recovery Session 1 30 mins 20–25 b/min below %HRR at VT
Phase 3 Maintenance n/a 27–52 Endurance Training 1 60 mins 10–20 b/min below %HRR at VT
Tempo Training & Resistance Training 2

TT: 35 mins

RT: 2 sets × 8–12 reps

TT: %HRR at VT ± 10 b/min

RT: 2 sets × 8–12 reps

Interval Training 1 4 × 4 minsb 85–95% HRpeak

Abbreviations: %HRR Percentage of heart rate reserve, 1RM One repetition max, HRpeak Heart rate peak, IT Interval training, RT Resistance training, TT Tempo training, VT Ventilatory threshold

aIntensity reduced by 5% from values reported in table during the week following chemotherapy administration

bOnly duration for work phase of intervals is reported – duration for recovery phase was 3 min of light-intensity cycling