Table 2.

Technical parameters of radiotherapy for lentigo maligna and lentigo maligna melanoma

First author	RT techniques	RT dose and fractionation	Margin
Lazarevic [10]	Grenz or soft x-rays (10–30 kV)	42–120 Gy in 3–13 fx, 3–4 day intervals	15 mm
Lamoureux [11]	Superficial x-rays («contact therapy»), 30–150 kV	40 Gy in 10 fx, 2x/week; or 39 Gy in 13 fx, 3x/week	5–10 mm
Hedblad [12]	Grenz rays (10 kV)	100–160 Gy, in 6 fx, 2x/week	10 mm
Lee [13]	Superficial x-rays	50 Gy in 20 fx	n.a.
Zalaudek [14]	Grenz rays, 10 kV	120 Gy in 6 fx	at least 5 mm
Farshad [15]	Grenz rays (12 kV, 107 patients) or superficial X-rays (20 to 50 kV, 57 patients)	12 kV: 100–120 Gy, 10–12 fx, 2x/week; 20–50 kV: 42–54 Gy, 7–9 fx, 2x/week	7–10 mm
Schmid-Wendter [16]	Grenz rays (14.5 kV) excision of the nodular part of LMM before RT	100 Gy, 10 fx, 5x/week	5–20 mm
Christie [17]	Superficial x-rays (100 kV)	44 Gy in 11 daily fx or 57.5 Gy in 23 daily fx	at least 10 mm
Tsang [18]	Superficial/ orthovoltage x-rays (100–250 kV)	35 Gy in 5 daily fx, 45 Gy in 10 daily fx or 50 Gy in 15 daily fractions	5–10 mm
Harwood [19]	Superficial/orthovoltage x-rays (LM: 100 kV; LMM: 125–175 kV)	35 Gy in 5 daily fx, 45 Gy in 10 daily fx, 50 Gy in 10–20 daily fx	at least 10 mm
Richter [20]	LM: Grenz rays (9 kV) or superficial x-rays (48.5 kV) LMM: superficial x-rays (26–38 kV)	LM: 10,000 R in 5–10 fx LMM: 6000–10,000 R in 12–20 fx	n.a.
Kopf [21]	Grenz rays (12 kV)	10,000 R in 5 fx, 3–4 day intervals	5 mm
Braun-Falco [22]	Grenz rays (14.5 kV)	10,000 R in 5–10 daily fx	n.a.
Arma-Szlachcic [23]	LM: Grenz rays (12 kV); LMM: Grenz rays or superficial x-rays (50–60 kV)	LM: most commonly 10,000–12,000 R in 5–6 fx every 5–7 days; LMM: various schedules	n.a.

Fx Radiotherapy fraction; LM Lentigo maligna; LMM Lentigo maligna melanoma; M Melanoma (not further specified); n.a. Not available