Table 3.
Achieved CR | Did not achieve CR | |||
---|---|---|---|---|
Glasdegib + LDAC n = 15 |
LDAC alone n = 1 |
Glasdegib + LDAC n = 63 |
LDAC alone n = 37 |
|
Median OS, months (95% CI) | 26.1 (12.3–34.6) | 12.9 (N/E–N/E) | 5.0 (3.5–8.3) | 4.1 (1.9–5.3) |
Survival probability, % (95% CI) | ||||
6 months | 100 (100–100) | 100 (100–100) | 49.5 (36.3–61.5) | 31.5 (17.2–47.0) |
12 months | 86.7 (56.4–96.5) | 100 (100–100) | 27.3 (16.7–39.0) | 5.7 (1.0–16.8) |
Deaths, n (%) | ||||
Cause of death: disease under study | 10 (66.7) | 1 (100) | 49 (77.8) | 28 (75.7) |
CI confidence interval, CR complete remission, LDAC low-dose cytarabine, N/E not evaluable, OS overall survival