Table 1. Patient and Treatment Characteristics.
BCL-U: B-cell lymphoma - unclassifiable; BIA-ALCL: breast implant-associated anaplastic large T-cell lymphoma; CLL/SLL: chronic lymphocytic leukemia/small lymphocytic leukemia; DLBCL: diffuse large B-cell lymphoma; ECOG: Eastern Cooperative Oncology Group
| Characteristics | All Patients n (%) | Indolent n (%) | Aggressive n (%) | P-value |
| Age (year), median (range) | 66 (34 – 95) | 66 (34 – 83) | 67 (49 – 95) | 0.46 |
| Age > 65 | 21 (58.3) | 12 (52.2) | 9 (69.2) | 0.48 |
| Male | 1 (2.8) | 0 (0) | 1 (7.7) | 0.36 |
| Female | 35 (97.2) | 23 (100) | 12 (92.3) | 0.47 |
| White ethnicity | 35 (97.2) | 22 (95.7) | 13 (100) | 1 |
| African American | 1 (2.8) | 1 (4.3) | 0 (0) | 0.65 |
| Clinical presentation at diagnosis | ||||
| Abnormal screening mammogram | 22 (61.1) | 18 (78.3) | 4 (30.8) | 0.005 |
| Breast lump/swelling | 14 (38.9) | 5 (21.7) | 9 (69.2) | 0.005 |
| B-symptoms | 2 (5.6) | 1 (4.3) | 1 (7.7) | 0.67 |
| ECOG performance score at diagnosis | 0.31 | |||
| 0 or 1 | 34 (94.4) | 22 (95.7) | 12 (92.3) | |
| 2 | 1 (2.8) | 1 (4.3) | 0 (0) | |
| 3 | 1 (2.8) | 0 (0) | 1 (7.7) | |
| Laterality of tumor | 0.69 | |||
| Right | 14 (38.9) | 9 (39.1) | 5 (38.5) | |
| Left | 17 (47.2) | 10 (43.5) | 7 (53.8) | |
| Bilateral | 5 (13.9) | 4 (17.4) | 1 (7.7) | |
| Stage at diagnosis | 0.74 | |||
| IE | 27 (75.0) | 18 (78.3) | 9 (69.2) | |
| IIE | 6 (16.7) | 3 (13.0) | 3 (23.1) | |
| IV | 3 (8.3) | 2 (8.7) | 1 (7.7) | |
| Histologic type | – | |||
| Marginal zone | 12 (33.3) | 12 (52.2) | 0 (0) | |
| Diffuse large B cell lymphoma | 9 (25.0) | 0 (0) | 9 (69.2) | |
| Follicular lymphoma | 7 (19.4) | 7 (30.4) | 0 (0) | |
| CLL/SLL | 3 (8.3) | 3 (13.0) | 0 (0) | |
| BIA-ALCL | 2 (5.6) | 0 (0) | 2 (15.4) | |
| BCL-U (DLBCL or Burkitt lymphoma) | 2 (5.6) | 0 (0) | 2 (15.4) | |
| Nodular sclerosing Hodgkin lymphoma | 1 (2.8) | 1 (4.3) | 0 (0) | |
| Treatment types | ||||
| Observation | 6 (16.7) | 6 (26.1) | 0 (0) | 0.07 |
| Chemotherapy only | 9 (25.0) | 6 (26.1) | 3 (23.1) | 0.84 |
| Radiotherapy only | 7 (19.4) | 5 (21.7) | 2 (15.4) | 0.64 |
| Surgery only | 2 (5.6) | 1 (4.3) | 1 (7.7) | 1 |
| Surgery/chemotherapy | 2 (5.6) | 1 (4.3) | 1 (7.7) | 1 |
| Chemotherapy/radiotherapy | 8 (22.2) | 2 (8.7) | 6 (46.2) | 0.009 |
| Surgery/radiotherapy | 1 (2.8) | 1 (4.3) | 0 (0) | 1 |
| Surgery/chemotherapy/radiotherapy | 1 (2.8) | 1 (4.3) | 0 (0) | 1 |