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. 2020 Jun 14;12(6):e8611. doi: 10.7759/cureus.8611

Table 1. Patient and Treatment Characteristics.

BCL-U: B-cell lymphoma - unclassifiable; BIA-ALCL: breast implant-associated anaplastic large T-cell lymphoma; CLL/SLL: chronic lymphocytic leukemia/small lymphocytic leukemia; DLBCL: diffuse large B-cell lymphoma; ECOG: Eastern Cooperative Oncology Group

Characteristics All Patients  n (%) Indolent  n (%) Aggressive  n (%) P-value
Age (year), median (range) 66 (34 – 95) 66 (34 – 83) 67 (49 – 95) 0.46
Age > 65 21 (58.3) 12 (52.2) 9 (69.2) 0.48
Male  1 (2.8) 0 (0) 1 (7.7) 0.36
Female  35 (97.2) 23 (100) 12 (92.3) 0.47
White ethnicity 35 (97.2) 22 (95.7) 13 (100) 1
African American 1 (2.8) 1 (4.3) 0 (0) 0.65
Clinical presentation at diagnosis        
     Abnormal screening mammogram 22 (61.1) 18 (78.3) 4 (30.8) 0.005
     Breast lump/swelling 14 (38.9) 5 (21.7) 9 (69.2) 0.005
     B-symptoms 2 (5.6) 1 (4.3) 1 (7.7) 0.67
ECOG performance score at diagnosis       0.31
     0 or 1 34 (94.4) 22 (95.7) 12 (92.3)  
     2 1 (2.8) 1 (4.3) 0 (0)  
     3 1 (2.8) 0 (0) 1 (7.7)  
Laterality of tumor       0.69
     Right 14 (38.9) 9 (39.1) 5 (38.5)  
     Left 17 (47.2) 10 (43.5) 7 (53.8)  
     Bilateral 5 (13.9) 4 (17.4) 1 (7.7)  
Stage at diagnosis       0.74
     IE 27 (75.0) 18 (78.3) 9 (69.2)  
     IIE 6 (16.7) 3 (13.0) 3 (23.1)  
     IV 3 (8.3) 2 (8.7) 1 (7.7)  
Histologic type      
     Marginal zone 12 (33.3) 12 (52.2) 0 (0)  
     Diffuse large B cell lymphoma 9 (25.0) 0 (0) 9 (69.2)  
     Follicular lymphoma 7 (19.4) 7 (30.4) 0 (0)  
     CLL/SLL 3 (8.3) 3 (13.0) 0 (0)  
     BIA-ALCL 2 (5.6) 0 (0) 2 (15.4)  
     BCL-U (DLBCL or Burkitt lymphoma) 2 (5.6) 0 (0) 2 (15.4)  
     Nodular sclerosing Hodgkin lymphoma 1 (2.8) 1 (4.3) 0 (0)  
Treatment types        
     Observation 6 (16.7) 6 (26.1) 0 (0) 0.07
     Chemotherapy only 9 (25.0) 6 (26.1) 3 (23.1) 0.84
     Radiotherapy only 7 (19.4) 5 (21.7) 2 (15.4) 0.64
     Surgery only 2 (5.6) 1 (4.3) 1 (7.7) 1
     Surgery/chemotherapy 2 (5.6) 1 (4.3) 1 (7.7) 1
     Chemotherapy/radiotherapy 8 (22.2) 2 (8.7) 6 (46.2) 0.009
     Surgery/radiotherapy 1 (2.8) 1 (4.3) 0 (0) 1
     Surgery/chemotherapy/radiotherapy 1 (2.8) 1 (4.3) 0 (0) 1