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. Author manuscript; available in PMC: 2020 Jul 15.
Published in final edited form as: Acc Chem Res. 2019 Apr 11;52(5):1148–1159. doi: 10.1021/acs.accounts.8b00674

Figure 8.

Figure 8.

(a) NMR structure of PS1 (PDB-ID 5tgy). (b) X-ray structure of 4DH2 (PDB-ID 5wlm) and close-view of the tetranuclear zinc cluster (histidines have been hidden for clarity). (c) Rocker tetrameric model (PDB-ID 2muz, 4p6j), depicted in a membrane (gray rectangle).