Table 3.
Pulmonary exacerbations observed using different definitions, ranked by incidence.
| Exacerbation definition | Description | Exacerbations, N (% of RE) | Subjects, N (%) |
|---|---|---|---|
| Any Antimicrobial Treatment (AT) | RE treatment with any antimicrobial | 596 (79.4%) | 211 (77.6%) |
| Investigator Assessment | Investigator opinion that RE was a pulmonary exacerbation | 352 (46.9%) | 172 (63.2%) |
| Modified Fuchs | RE with ≥4 Fuchs criteria recorded | 254 (33.8%) | 138 (50.7%) |
| Expanded Fuchs | Any antimicrobial treatment of RE with ≥4 Fuchs criteria recorded | 231 (30.8%) | 128 (47.1%) |
| IV Antimicrobial Treatment (IVAT) | RE treatment with IV antimicrobial | 192 (25.6%) | 106 (39.0%) |
| Original Fuchs | IV antimicrobial treatment of RE with ≥4 Fuchs criteria recorded | 106 (14.1%) | 71 (26.1%) |