Table 1.
Clinical data and follow-up data of 23 cases of pregnant women infected with nCoV in 2019.
| Clinical features (23 pregnancies) | |
| Maternal age (years) | Varies from 16 to 40 years with mean of 29.3 ± 2.9 |
| Ethnicity | 16 Asian, 3 Eastern Europe, 1 Black, 3 White British |
| Pregnancy comorbidities (11 pregnancies) | DM/gestational diabetes (4), acute kidney injury (3), Asthma (2), hyperthyroidism (1), pylonephritis (1) |
| Adverse pregnancy outcome (17 pregnancies) | Preterm delivery (7), RFM (6), PPROM (4), preeclampsia (2), HELLP (2), DIC (2), OC (1), fetal distress (1) |
| meconium (2), missed miscarriage (1) | |
| Signs and symptoms (23 patients) | |
| Antenatal/intrapartum Pyrexia | 14 antenatal, 2 intrapartum |
| Postpartum Pyrexia | 1 patient (day 1 post c-section) |
| Shortness of breath, chest pain | 8 patients |
| Dry cough | 12 patients |
| Diarrhea, abdominal pain | 4 patients |
| Chest x ray/ Chest CT scan evidence of 2019-nCoV pneumonia | Chest x ray positive in 20 patients, Chest CT positive in 1 patient |
| Delivery process (19 patients) | |
| Gestation at delivery | Varies from 29 weeks 3 days up to 40 weeks 2 days with mean of 38.7 ± 1.4 |
| Delivery Method | C-section in 16 patients, normal vaginal delivery in 3 patients |
| Steroids | Adminstrated in 5 patients (2 prior to ELCS < 39 weeks; 3 for PPROM) |
| Indication for c-section | 3 ELCS, 13 EMCS (2 fetal distress, 4 failure to progress, 7 maternal request/PPROM/sepsis) |
| Neonatal outcome (20 neonates [1twins]) | |
| Apgars at 1 & 5 min | (9, 10) in all of them except 1 baby (3,7) |
| Birthweight | Varies from 2240 to 4450 g with mean of 3139 g ± 437 |
| Neonatal outcome | Bacterial pneumonia (1), fetal asphyxia (Resuscitated using positive pressure/endotracheal tube) (1) |
| Neonatal rt-PCR for SARS-CoV | Negative |
| IV Antibiotics | Adminstrated in 4 neonates with potential infection |
| Maternal outcome (19 patients) | |
| Antenatal/intrapartum | Pylonephritis (1), PPH (1) |
| Postnatal | PPH (1), ECMO (1), death (1) |
Abbreviations: ECMO-Extracorporeal membrane oxygenation; OC- obstetrics Cholestasis; PPROM- Preterm premature rupture of the membranes; SGA-small for gestational age; DIC-disseminated intravascular coagulation; ELCS- elective c-section; EMCS- emergency c-section; CVA- cerebrovascular accident; HTN- hypertension.