Table 1.
Baseline covariate summaries from the UNCOVER and FIXTURE trials†
| Covariate | Values for | Values for | Values for | Values for |
|---|---|---|---|---|
| UNCOVER‐1 | UNCOVER‐2 | UNCOVER‐3 | FIXTURE | |
| (N=1296) | (N=1219) | (N=1339) | (N=1306) | |
| Age, years | 45.7 (12.9) | 45.0 (13.0) | 45.7 (13.1) | 44.5 (12.9) |
| Body surface area, %‡ | 27.7 (17.3) | 26.0 (16.5) | 28.3 (17.1) | 34.4 (18.9) |
| Duration of psoriasis, years‡ | 19.6 (11.9) | 18.7 (12.5) | 18.2 (12.2) | 16.5 (12.0) |
| Baseline PASI score | 20.1 (8.0) | 19.6 (7.2) | 20.9 (8.2) | 23.7 (10.2) |
| Previous systemic treatment(%) ‡ | 71.3 | 64.2 | 57.1 | 64.0 |
| Psoriatic arthritis (%)‡ | 26.3 | 23.6 | 20.5 | 14.7 |
| Male (%) | 68.1 | 67.0 | 68.2 | 71.1 |
| Weight, kg‡ | 92.2 (23.8) | 91.6 (22.2) | 91.2 (23.5) | 83.3 (20.8) |
†Reported sample size for the UNCOVER‐2 and UNCOVER‐3 trials after removing two individuals from each study with missing weight. The statistics are the mean (with standard deviation in parentheses) unless otherwise specified.
‡Covariate considered a potential effect modifier, to be included in population adjustment.