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. 2020 Jul 8;11:612. doi: 10.3389/fphys.2020.00612

TABLE 2.

Table describing the mean and standard error of baseline measurements of myocytes from mouse, rat, guinea pig, and human hearts measurements of functional parameters.

Simple statistics Hierarchical statistics p values

Sample Prep. n % TTP90 TTB90 % (ICC) TTP90 (ICC) TTB90 (ICC) Suit. p values
Rat 5 226 3.670 ± 0.180 0.056 ± 0.001 0.182 ± 0.003 3.148 ± 0.730 (18.5) 0.048 ± 0.008 (28.2) 0.151 ± 0.021 (16.7) YYY Rat vs. rat + fura
Rat + Fura 7 510 4.751 ± 0.137 0.057 ± 0.001 0.222 ± 0.003 4.026 ± 0.518 0.053 ± 0.006 0.206 ± 0.015 parameter Simple Hierarchical
% < 0.0001 0.051
TTP90 0.55 0.64
TTB90 < 0.0001 0.06
Mouse LV 3 165 2.539 ± 0.191 0.048 ± 0.001 0.305 ± 0.012 2.854 ± 0.930 (30.9) 0.049 ± 0.002 (3.4) 0.338 ± 0.006 (30.3) YNY Mouse LV vs. mouse RV
Mouse RV 3 84 3.250 ± 0.346 0.054 ± 0.002 0.391 ± 0.023 3.164 ± 0.937 0.054 ± 0.002 0.406 ± 0.061 parameter Simple Hierarchical
% 0.0519 0.82
TTP90 0.0013 0.15
TTB90 0.0002 0.46
Guinea Pig 1 71 5.213 ± 0.360 0.228 ± 0.010 0.627 ± 0.021
Human LV 1 4 3.202 ± 0.994 0.244 ± 0.040 0.687 ± 0.074
Human LA 1 14 0.430 ± 0.161 0.062 ± 0.016 0.446 ± 0.153
Human RA 1 5 2.500 ± 0.832 0.218 ± 0.121 0.637 ± 0.131

The table describes the statistics generated by conventional and advanced (hierarchical) approaches and includes the results of statistical significance between appropriate samples. The column (suit.) describes whether the advanced test (Y) or the conventional test (N) is sufficient in each case. Results from several preparations are presented using simple statistics (mean ± standard deviation) and using hierarchical statistics (mean ± standard deviation and ICC). The p values column presents the calculations of p using Student’s t test or the hierarchical method. Significance is commonly reduced using hierarchical statistics.