TABLE 4.
Distribution of genetic variants related to carotenoid metabolism and transport1
| Gene | SNP | Chromosome (loc) | Genotypes (n) | ||
|---|---|---|---|---|---|
| LPL | rs7841189* | 8 (19845376) | TT (1) | TC (4) | CC (10) |
| ELOVL2 | rs9468304* | 6 (11042165) | GG (7) | AG (6) | AA (2) |
| SOD2 | rs9365046 | 6 (159756737) | GG (13) | AG (2) | — |
| ELOVL2 | rs911196* | 6 (10990751) | AA (7) | AC (6) | CC (2) |
| BCO1 | rs6564851* | 16 (81264597) | GG (4) | TG (9) | TT (2) |
| CD36 | rs4112274 | 7 (80167254) | CC (11) | TC (4) | — |
| ABCG2 | rs1871744 | 4 (89039629) | TT (13) | TC (2) | — |
| LPL | rs17482753* | 4 (19832646) | GG (11) | TG (3) | TT (1) |
| MTTP | rs17029173 | 4 (100509321) | TG (3) | TT (12) | — |
| SCARB1 | rs1672879 | 12 (125281102) | CC (13) | AC (2) | — |
| SCARB1 | rs11057841 | 12 (125316743) | CC (11) | TC (4) | — |
| APOB | rs1042031 | 2 (21225753) | GG (11) | AG (4) | — |
| ABCB1 | rs10248420 | 7 (87164986) | AA (8) | AG (7) | — |
1
SNP = single nucleotide polymorphism;LPL = lipoprotein lipase; ELOVL2 = ELOVL fatty acid elongase 2; SOD2 = superoxide dismutase 2; BCO1 = beta-carotene oxygenase 1; CD36 = CD36 molecule; ABCG2 = ATP binding cassette subfamily G member 2; MTTP = microsomal triglyceride transfer protein; SCARB1 = scavenger receptor class B member 1; APOB = apolipoprotein B; ABCB1 = ATP binding cassette subfamily B member 1.
*
SNP analyzed by combining 2 of the 3 genotypes owing to the low representation of 1 genotype in this sample population.