TABLE 1.

List of parameters used by operations in the Segmentation stage of our motivating application and their range values. The search space formed is of about 21 trillion points

Parameter	Description	Range values
B/G/R	Background detection thresholds	[210, 220, …, 240]
T1/T2	Red blood cell thresholds	[2.5, 3.0, …, 7.5]
G1	Thresholds to identify candidate nuclei	[5, 10, …, 80]
G2	Thresholds to identify candidate nuclei	[2, 4, …, 40]
MinSize (minS)	Candidate nuclei area threshold	[2, 4, …, 40]
MaxSize (maxS)	Candidate nuclei area threshold	[900, …, 1500]
MinSizePl(minSPL)	Area threshold before watershed	[5, 10, …, 80]
MinSizeSeg (maxSS)	Area threshold in final output	[2, 4, …, 40]
MaxSizeSeg (minSS)	Area threshold in final output	[900, …, 1500]
FillHoles (FH)	Propagation neighborhood	[4-conn, 8-conn]
MorphRecon (RC)	Propagation neighborhood	[4-conn, 8-conn]
Watershed (WConn)	Propagation neighborhood	[4-conn, 8-conn]