Table 5.
Passive property values and comparisons for GABAergic sPSC and mPSC recordings in GnRH-GFP-4Di mice (mean ± SEM, p values from two-tailed unpaired Student’s t test with or without Welch correction)
| Saline | CNO | p value* | t | df | |
|---|---|---|---|---|---|
| Spontaneous GABAergic PSCs | |||||
| n | 10 | 8 | |||
| Series resistance (MΩ) | 12.8 ± 0.9 | 11.4 ± 0.7 | 0.260 | 1.167 | 16 |
| Input resistance (MΩ) | 602.9 ± 41.6 | 660.4.6 ± 53.6 | 0.402 | 0.861 | 16 |
| Holding current (pA) | –54.0 ± 7.3 | –49.0 ± 6.9 | 0.629 | 0.492 | 16 |
| Capacitance (pF) | 14.4 ± 1.2 | 13.9 ± 0.5 | 0.710 | 0.380 | 12.4 |
| Miniature GABAergic PSCs | |||||
| n | 11 | 7 | |||
| Series resistance (MΩ) | 13.2 ± 1.1 | 12.6 ± 1.3 | 0.760 | 0.310 | 16 |
| Input resistance (MΩ) | 681.0 ± 62.4 | 734.4.4 ± 116.9 | 0.665 | 0.441 | 16 |
| Holding current (pA) | –49.4 ± 4.3 | –53.8 ± 10.5 | 0.660 | 0.440 | 16 |
| Capacitance (pF) | 13 ± 1.1 | 14.7 ± 1.1 | 0.609 | 0.522 | 16 |
*
compares listed passive properties between saline and CNO groups.