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Changes in the levels of lysosome proteins in TMEM106B-deficient mice. Western blot analysis of lysosomal proteins in wild-type and Tmem106b−/− frontal cortex lysates (A and B: 5-month-old, Δ341bp; C and D: 10-month-old, Δ7bp). n = 3 (two females, one male each genotype), *P < 0.05, paired t-test with wild-type littermate controls.
