Table 2.
Clinical data at presentation of the study population by age-dependent categories
| Patients N = 1379 n (%) |
18–44 years, N = 250 n (%) |
45–54 years, N = 246 n (%) |
55–64 years, N = 247 n (%) |
65–74 years, N = 237 n (%) |
75–84 years, N = 235 n (%) |
> = 85 years, N = 164 n (%) |
P value | |
|---|---|---|---|---|---|---|---|---|
| Acute episode clinical data | ||||||||
| Time of evolution, days [median (IQR)] | 7 (3–9) | 3 (6–7) | 4 (7–9) | 4 (7–9) | 3 (7–10) | 4 (7–8) | 2.5 (4–7) | 0.657 |
| Cough | 981 (71.1) | 196 (78.1) | 170 (69.1) | 189 (76.5) | 168 (70.9) | 158 (67.2) | 100 (61.0) | < 0.001 |
| Fever | 1104 (80.0) | 208 (83.2) | 204 (82.9) | 207 (83.8) | 193 (81.4) | 180 (76.6) | 111 (67.7) | < 0.001 |
| Dyspnoea | 653 (47.3) | 120 (47.8) | 121 (49.2) | 123 (49.8) | 115 (48.5) | 100 (42.6) | 74 (45.1) | 0.222 |
| Chest pain | 158 (11.4) | 38 (15.1) | 36 (14.6) | 34 (13.8) | 31 (13.1) | 11 (4.7) | 8 (4.9) | < 0.001 |
| Diarrhoea | 275 (19.9) | 42 (16.8) | 56 (22.8) | 62 (25.1) | 59 (24.9) | 39 (16.6) | 16 (9.8) | 0.056 |
| Nausea and vomiting | 137 (9.9) | 35 (13.9) | 22 (8.9) | 27 (10.9) | 30 (12.7) | 18 (7.7) | 5 (3.0) | 0.002 |
| Headache | 148 (10.7) | 41 (16.3) | 41 (16.7) | 32 (13.0) | 17 (7.2) | 9 (3.8) | 8 (4.9) | < 0.001 |
| Confusion | 38 (2.8) | 0 (0.0) | 1 (0.4) | 1 (0.4) | 8 (3.4) | 12 (5.1) | 16 (9.8) | < 0.001 |
| Anosmia | 57 (4.1) | 15 (6.0) | 23 (9.3) | 10 (4.0) | 8 (3.4) | 0 (0.0) | 1 (0.6) | < 0.001 |
| Dysgeusia | 59 (4.3) | 12 (4.8) | 18 (7.3) | 15 (6.1) | 11 (4.6) | 2 (0.9) | 1 (0.6) | < 0.001 |
| Myalgia | 313 (22.7) | 73 (29.2) | 72 (29.3) | 74 (30.0) | 40 (16.9) | 35 (14.9) | 18 (11.0) | < 0.001 |
| Asthenia | 449 (32.5) | 63 (25.2) | 79 (32.1) | 82 (33.2) | 90 (38.0) | 82 (34.9) | 53 (32.3) | 0.033 |
| Sore throat | 89 (6.4) | 27 (10.8) | 19 (7.7) | 18 (7.3) | 9 (3.8) | 12 (5.1) | 4 (2.4) | < 0.001 |
| Rhinorrhoea | 27 (2.0) | 12 (4.8) | 7 (2.8) | 4 (1.6) | 0 (0.0) | 1 (0.4) | 3 (1.8) | 0.001 |
| Skin lesions | 4 (0.3) | 2 (0.8) | 0 (0.0) | 0 (0.0) | 1 (0.4) | 1 (0.4) | 0 (0.0) | 0.484 |
| Presyncope or syncope | 68 (4.9) | 0 (0.0) | 11 (4.5) | 7 (2.8) | 14 (5.9) | 20 (8.5) | 16 (9.8) | < 0.001 |
| Physical data | ||||||||
| Oxygen saturation, % [mean (SD)] | 94 (6.6) | 97 (3.1) | 96 (5.7) | 94 (6.2) | 93 (6.5) | 91 (7.8) | 91 (7.4) | < 0.001 |
| Body temperature, °C [mean (SD)] | 37.5 (2.9) | 37.7 (4.2) | 37.4 (1.0) | 37.7 (4.0) | 37.3 (0.9) | 37.5 (3.4) | 37.1 (0.7) | 0.002 |
| SBP, mmHg [mean (SD)] | 130 (20.8) | 125 (17.8) | 129 (18.2) | 129 (19.1) | 132 (19.9) | 128 (22.1) | 134 (24.8) | 0.043 |
P value for lineal trend. Numbers in bold mean value P < 0.05
SBP systolic blood pressure, IQR interquartile range, SD standard deviation