Table 2.
Association of five personality traits with incidence of mild cognitive impairment (MCI) and motoric cognitive risk syndrome (MCR).
| Incident cases/Total, n |
Adjusted HR (95% CI)a, p-value | |
|---|---|---|
| Extraversion | ||
| MCI | 69/466 | 1.00 (0.97-1.04), 0.860 |
| Amnestic MCI | 28/510 | 0.98 (0.93-1.04), 0.463 |
| Non-amnestic MCI | 41/480 | 1.02 (0.97-1.08), 0.395 |
| MCR | 38/500 | 0.98 (0.93-1.03), 0.450 |
| Agreeableness | ||
| MCI | 69/466 | 1.04 (0.99-1.10), 0.147 |
| Amnestic MCI | 28/510 | 1.02 (0.94-1.11), 0.603 |
| Non-amnestic MCI | 41/480 | 1.06 (0.98-1.13), 0.138 |
| MCR | 38/500 | 1.03 (0.96-1.11), 0.453 |
| Conscientiousness | ||
| MCI | 69/466 | 1.00 (0.96-1.05), 0.907 |
| Amnestic MCI | 28/510 | 0.99 (0.93-1.06), 0.783 |
| Non-amnestic MCI | 41/480 | 1.01 (0.96-1.07), 0.692 |
| MCR | 38/500 | 0.98 (0.92-1.03), 0.407 |
| Neuroticism | ||
| MCI | 69/466 | 1.03 (0.99-1.07), 0.104 |
| Amnestic MCI | 28/510 | 0.99 (0.93-1.06), 0.847 |
| Non-amnestic MCI | 41/480 | 1.06 (1.01-1.11), 0.020 |
| MCR | 38/500 | 0.99 (0.94-1.05), 0.790 |
| Openness | ||
| MCI | 69/466 | 0.99 (0.95-1.03), 0.543 |
| Amnestic MCI | 28/510 | 1.00 (0.95-1.06), 0.912 |
| Non-amnestic MCI | 41/480 | 0.98 (0.93-1.03), 0.351 |
| MCR | 38/500 | 0.94 (0.89-0.99), 0.015 |
a
Hazard ratios (HR) with 95% confidence intervals (CI) are adjusted for age, sex, education and summary multi-morbidity score in all models.