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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Neuroscience. 2020 May 22;440:85–96. doi: 10.1016/j.neuroscience.2020.05.021

Figure 2.

Figure 2.

Cell-attached recording of PCs of the systematic Btbd9 KO mice (n=6) and their WT littermates (n=6). (A) Representative spontaneous activity traces of WT and Btbd9 KO in acute brain slides. The percentage of non-tonic cells showed a significant increase with Btbd9 knockout. (B) Both spontaneous firing frequency and coefficients of variation were not changed between Btbd9 KO (n=49) and WT (n=44) PCs. (C) The spontaneous firing frequency was significantly higher in Btbd9 KO tonic cells (n=24) compared with the WTs (n=36), while the coefficient of variation was not changed in Btbd9 KO tonic cells. (D) There was no change in either spontaneous firing frequency or regularity between Btbd9 KO non-tonic PCs (n=30) and the WT non-tonic PCs (n=13). The data in B-D are presented as the median with the 95% confidence intervals (CIs). *, p ≤ 0.05.