Table 2.
Baseline of the Pooled Data, and Percent Change at 12 months in QCT Variables, by Group
| Variable | Total baseline (n = 66) | Control %ΔV5 (n = 13) | Low magnitude (n = 13) %ΔV5 | High magnitude %ΔV5 (n = 17) | Low rate %ΔV5 (n = 12) | High rate %ΔV5 (n = 11) |
|---|---|---|---|---|---|---|
| Ultradistal | ||||||
| iBV (cm3) | 3.84 ± 0.40 | −1.17 ± 2.51 | 0.75 ± 2.14 | −0.01 ± 2.23 | −0.29 ± 1.29 | 0.35 ± 1.86 |
| iBMC (g) | 0.91 ± 0.15 | −1.31 ± 2.68 | 0.46 ± 1.52 | −0.33 ± 2.03 | 2.73 ± 2.07 | 3.42 ± 2.21 |
| iBMD (g/cm3) | 0.24 ± 0.03 | −0.59 ± 2.08 | −0.23 ± 0.96 | −0.33 ± 1.19 | 3.03 ± 1.08 | 3.07 ± 1.46 |
| ecBV (cm3) | 1.99 ± 0.15 | −0.41 ± 1.49 | 0.89 ± 1.39 | 0.34 ± 1.58 | −0.01 ± 1.25 | 0.41 ± 1.46 |
| ecBMC (g) | 0.63 ± 0.18 | −0.19 ± 4.87 | 0.12 ± 2.46 | −0.10 ± 2.62 | 4.84 ± 3.64 | 4.45 ± 3.47 |
| ecBMD (g/cm3) | 0.31 ± 0.08 | 0.21 ± 4.52 | −0.74 ± 2.79 | −0.43 ± 2.59 | 4.85 ± 3.46 | 4.03 ± 3.30 |
| Total | ||||||
| iBV (cm3) | 12.96 ± 1.55 | −0.06 ± 0.47 | −0.25 ± 0.52 | −0.13 ± 0.45 | 0.16 ± 0.64 | 0.38 ± 0.41 |
| iBMC (g) | 5.10 ± 0.60 | −0.23 ± 1.20 | −0.45 ± 0.80 | −0.19 ± 0.78 | 1.97 ± 0.86 | 1.93 ± 0.75 |
| iBMD (g/cm3) | 0.39 ± 0.04 | −0.17 ± 1.14 | −0.19 ± 0.58 | −0.06 ± 0.78 | 1.81 ± 0.63 | 1.55 ± 0.86 |
| ecBV (cm3) | 8.24 ± 0.72 | 0.17 ± 0.71 | −0.07 ± 0.57 | 0.18 ± 0.44 | 0.45 ± 0.62 | 0.35 ± 0.64 |
| ecBMC (g) | 4.09 ± 0.55 | 0.15 ± 1.78 | −0.26 ± 1.11 | 0.00 ± 1.01 | 2.06 ± 1.40 | 1.72 ± 1.37 |
| ecBMD (g/cm3) | 0.50 ± 0.05 | −0.02 ± 1.28 | −0.20 ± 0.76 | −0.18 ± 0.98 | 1.60 ± 0.84 | 1.36 ± 0.83 |
| Ultradistal strength | ||||||
| CSA (cm2) | 4.15 ± 0.42 | −0.67 ± 1.67 | 0.65 ± 1.45 | 0.00 ± 1.48 | −0.26 ± 1.23 | 0.35 ± 1.75 |
| CSI (g2/cm4) | 0.24 ± 0.07 | −1.81 ± 4.40 | 0.18 ± 1.96 | −0.65 ± 2.85 | 5.90 ± 3.05 | 6.62 ± 3.26 |
| BSI (cm3) | 0.12 ± 0.03 | −0.59 ± 4.31 | 0.32 ± 1.90 | −0.29 ± 2.30 | 4.74 ± 2.44 | 4.81 ± 2.70 |
Data are shown as mean ± SD. Bold indicates significant regression coefficient representing contrast with control group for raw change. Baseline is for participants with follow‐up data available. %ΔV5 = percent change at visit 5.