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. Author manuscript; available in PMC: 2020 Jul 16.
Published in final edited form as: Genesis. 2020 Apr 7;58(7):e23364. doi: 10.1002/dvg.23364

FIGURE 2.

FIGURE 2

Visualization of cNCCs and overall heart development in control and NC-specific compound Foxc1;Foxc2 mutants at E14.5. (a) Control heart section displaying normal outflow tract septation between the Aorta (Ao) and pulmonary trunk (Pt). (b and c) Control heart sections displaying outflow tract septation with AP-2alpha positive cardiac neural crest cells (cNCCs) labeled in bright pink. (d–f) NC-Foxc1;Foxc2-DKO heart sections displaying persistent truncus arteriosus (PTA) with cNCCs labeled in green. Scale bars are 150 μm