Table 2.
Diagnostic value of in-hospital mortality of cTnI-ultra, CK-MB, MYO, NT-proBNP and Cr in COVID-19 patients.
| Biomarkers | AUC (95%CI) | Cutoff values | SE, % | SP, % | PPV (95%CI) | NPV (95%CI) |
|---|---|---|---|---|---|---|
| cTnI-ultra | 0.855 (0.798–0.912) | 0.020 | 67.3 | 88.7 | 54.4 (43.9–64.5) | 93.1 (90.1–95.3) |
| CK-MB | 0.785 (0.710–0.859) | 2.190 | 63.5 | 85.8 | 47.3 (37.8–57.0) | 92.1 (89.1–94.4) |
| MYO | 0.809 (0.744–0.873) | 82.085 | 75.0 | 76.9 | 39.4 (32.7–46.5) | 93.9 (90.5–96.1) |
| NT-proBNP | 0.822 (0.761–0.884) | 340.00 | 84.6 | 68.4 | 34.9 (29.9–40.3) | 95.7 (92.1–97.7) |
| Cr | 0.624 (0.528–0.721) | 69.50 | 55.8 | 72.6 | 29.0 (22.7–36.1) | 89.1 (85.7–91.8) |
Abbreviation: cTnI-ultra, cardiac troponin I-ultra; CK-MB, creatinine kinase–myocardial band; MYO, myoglobin; NT-proBNP, N-terminal pro-B-type natriuretic peptide; Cr, creatinine; AUC, area under curve; SE, sensitivity; SP, specificity; PPV, Positive Predictive Value; NPV, negative predictive value; CI, confidence interval.