Table 5.
Clinical outcomes of neonates born from women infected by SARS-CoV-2.
Study | New-borns, n | Pre-term, n (%) | Mean (range) birthweight, g | Apgar score 1 min, range | Apgar score 5 min, range | Complication*, n (%) | SARS-CoV2 RNA | Death, n (%) | * |
---|---|---|---|---|---|---|---|---|---|
Li Y., et al. [2] | 1 | 0 | – | – | – | 0 (0.0) | 0 | 0 | – |
Chen H., et al. [3] | 9 | 4 (44.4) | 3011 (1880−3820) | 8−9 | 9−10 | 2 (22.2) | 0 (0.0) | 0 (0.0) | Low birthweight 2 |
Fan C., et al. [4] | 2 | 0 (0.0) | 3145 (2890−3400) | 9 | 10 | 2 (100) | 0 (0.0) | 0 (0.0) | Fever and abdominal distension and lymphopenia 1; pneumonia and lymphopenia 1 |
Chen Y., et al. [5] | 4 | 0 (0.0) | 3000 (3050−3800) | 7−8 | 8−9 | 2 (50.0) | 0/3 (0.0) | 0 (0.0) | Skin rash 2; Oedema 1; Transient tachypnoea of the newborn 1. |
Zhu H., et al. [6] | 10 | 6 (60.0) | 2423 (1520−3800) | 7−10 | 8−10 | 9 (90.0) | 0 (0.0) | 1 (10.0) | shortness of breath 6; fever 2; Rapid heart rate 1; Gastrointestinal symptoms 4; Infections 4; neonatal respiratory distress syndrome (NRDS) 2; pneumothorax 1 |
Zhang L., et al. [7] | 16 | 1 (6.3) | 3139 (2300−3750) | – | – | 3 (18.8) | 0/10 (0.0) | 0 (0.0) | Pneumoniae 3 |
Liu W., et al. [8] | 3 | 0 (0.0) | 3390 (3250−3670) | 8 | 9 | 2 (66.7) | 0 (0.0) | 0 (0.0) | Meconium Stained Amniotic Fluid (MSAF) 1; Slight decreased responsiveness and muscle tension 1. |
Wang X., et al. [9] | 1 | 1 | 1830 | 9 | 10 | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
Liu D., et al. [10] | 11 | – | – | 8 | 9 | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
Liu Y., et al. [15] | 10 | 6 (60.0) | – | – | – | – | – | 1 (10.0) | – |
Yu N., et al. [16] | 7 | 0 (0.0) | 3264 (3000−3500) | 8−9 | 9−10 | 1 (14.3) | 1/3 (33.3) | 0 (0.0) | SARS-CoV2 positivity with mild pulmonary infection. |
Zeng L., et al. [17] | 33 | 4 (12.1) | – | – | – | No individual data | 3 (9.1) | 0 (0.0) | Fever 2, SARS-Cov2 pneumoniae 3; Shortness of breath 4; Respiratory distress syndrome 4; Cyanosis 3; Feeding intolerance 3 |
Dong L., et al. [18] | 1 | 0 | 3120 | 9 | 10 | 1 | 0 (0.0) | 0 (0.0) | Abnormal cytokine test results 2 h after birth |