. 2020 Jul 6;24:92–98. doi: 10.1016/j.ctro.2020.07.001

Table 1.

Tumour response classification DRE: digital rectal examination; cCR: clinical complete response; PR: partial response; SD: stable disease; TRG: tumor regression grade.

	cCR	Near cCR	PR or SD
DRE	–No palpable Tumor		-Palpable hard sessile tumor
	-Rectal wall supple	-Rectal wall: firm	-Rectal wall: Hard induration
	–No ulceration	-Ulceration: superficial, smooth edge, regular fundus	-Ulceration: Irregular/deep
	–No nodularity	-Nodularity: Small-supple/firm	-Nodularity: hard or firm
Endoscopy	–No visible tumor and normal appearance of mucosa.		-Visible malignant tumor
Rigid rectoscopy	–No visible tumor and normal appearance of mucosa.		-Visible malignant tumor
Flexible colonoscopy or sigmoidoscopy	-Scar appearance -White scar -Radiation Erythematous mucositis -Small radiation Inflammatory vessels		-Ulceration: irregular and deep
MRI	TRG1	TRG2	TRG 3–4-5