Table 4.
Standardized regression coefficients of adjusted linear regression analyses with continuous baseline fat mass index (FMI), lean mass index (LMI), and their interaction explaining changes in health-related quality of life (HRQoL, RAND-36) domains
| HRQoL change | Fat mass index | Lean mass index | FMI × LMI interaction | |||
|---|---|---|---|---|---|---|
| β (95% CI) | p | β (95% CI) | p | β (95% CI) | p | |
| General health | − 0.13 (− 0.20 to − 0.06) | 0.001 | − 0.01 (− 0.09 to 0.08) | 0.90 | − 0.01 (− 0.06 to 0.05) | 0.84 |
| Physical functioning | − 0.11 (− 0.18 to − 0.04) | 0.002 | − 0.01 (− 0.09 to 0.07) | 0.80 | − 0.01 (− 0.05 to 0.05) | 0.94 |
| Role physical | − 0.13 (− 0.22 to − 0.05) | 0.003 | 0.01 (− 0.09 to 0.11) | 0.82 | 0.01 (− 0.05 to 0.07) | 0.67 |
| Bodily pain | − 0.08 (− 0.16 to 0.01) | 0.058 | − 0.07 (− 0.17 to 0.02) | 0.12 | 0.05 (− 0.01 to 0.11) | 0.075 |
| Mental health | − 0.02 (− 0.10 to 0.06) | 0.57 | − 0.07 (− 0.16 to 0.02) | 0.15 | − 0.03 (− 0.08 to 0.01) | 0.33 |
| Vitality | − 0.08 (− 0.16 to − 0.01) | 0.027 | − 0.04 (− 0.12 to 0.05) | 0.37 | 0.02 (− 0.03 to 0.08) | 0.41 |
| Role emotional | − 0.12 (− 0.20 to − 0.03) | 0.007 | 0.04 (− .06 to 0.14) | 0.40 | − 0.01 (− 0.06 to 0.06) | 0.94 |
| Social functioning | − 0.06 (− 0.14 to 0.03) | 0.19 | − 0.03 (− 0.13 to 0.07) | 0.51 | − 0.04 (− 0.10 to 0.02) | 0.24 |
| Physical component score | − 0.14 (− 0.22 to − 0.07) | < 0.001 | − 0.02 (− 0.11 to 0.06) | 0.58 | 0.02 (− 0.03 to 0.08) | 0.43 |
| Mental component score | − 0.03 (− 0.11 to 0.05) | 0.49 | − 0.02 (− 0.12 to 0.08) | 0.68 | − 0.03 (− 0.08 to 0.03) | 0.40 |
Independent variables included in the regression models: FMI, LMI, FMI × LMI interaction, sex, age, education, smoking, alcohol use, physical activity, severe long-term illness, and corresponding HRQoL domain at baseline
The values of the standardized regression coefficients above 0.10, 0.30, and 0.50 represent small, moderate and large effect sizes, respectively