Fig. 1.

The different expression of miR-221/222 in papillary thyroid carcinoma (PTC) and their adjacent normal tissue (ANT). Quantitative real-time polymerase chain reaction (qRT-PCR) was performed to detect the relative expression of miR-221/222 in PTC tissues and their ANT of PTC patients, n = 10. The results showed that miR-221/222 were up-regulated in PTC tissues, compared with their ANT (the fold-change of miR-221 was about 35, and that of miR-222 was about 23). The data were analyzed using student’s t-test. Red and black histograms represent ANT and PTC groups, respectively. Error bars indicate mean ± SD (**P < 0.01)