Fig. 6.

MiR-221/222 inhibits autophagy and apoptosis by ATG10. a, b WB was used to verify the effects of miR-221/222 inhibitor or miR-221/222 inhibitor and ATG10 siRNA on autophagy protein LC3II and P62. c Flow cytometry shows the effect of miR-221/222 inhibitor or miR-221/222 inhibitor and ATG10 siRNA on the apoptosis of PTC cells. The test was repeated independently in triplicates. Two-sample and other variance t-tests were used for treatment. (miR, microRNA; mimics, overexpression; inhibitor, interference; mimics NC, overexpression negative control; inhibitor NC, interference negative control)