TABLE 3.
Protection of and symptom severity in guinea pigs after challenge with A/GDMM/CHA/2013 strain.
Serial numberb | Groupsa |
||||||
1 | 2 | 3 | 4 | 5 | 6 | 7 | |
Protection | |||||||
1 | Proc | Pro | N-Pro | Pro | N-Pro | N-Pro | N-Pro |
2 | N-Prod | Pro | N-Pro | Pro | N-Pro | Pro | N-Pro |
3 | Pro | Pro | N-Pro | Pro | Pro | N-Pro | N-Pro |
4 | Pro | Pro | N-Pro | Pro | N-Pro | Pro | N-Pro |
Severity of symptoms | |||||||
1 | None | None | Severe | None | Severe | Severe | Severe |
2 | Severe | None | Severe | None | Severe | None | Severe |
3 | None | None | Severe | None | None | Severe | Severe |
4 | None | None | Severe | None | Severe | None | Severe |
Rate of protection (%) | 75 (3/4) | 100 (4/4) | 0(0/4) | 100 (4/4) | 25 (1/4) | 50 (2/4) | 0 (0/4) |
aGroups of the immunized guinea pigs. bSerial number of immunized guinea pigs in each group. cProtection, indicating no lesions on footpads other than the inoculated footpad. dNonprotection, indicating the appearance of a secondary lesion on any footpad other than the inoculated footpad.