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. 2020 Jul 9;8:538. doi: 10.3389/fcell.2020.00538

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Copyright © 2020 Liu, Hu, Li, Zhang, Wu, Liu, Wang, Zhang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ferroptosis is positively correlated with glioblastoma cell migration. (A) Analysis in the CGGA database showing the positive correlation between risk score and migration-related genes. (B–D) Images under a light microscope and a summary of data showing that treatment with erastin (50 μM) increased the migration of U251MG, U251TR, U87MG, and U87TR cells relative to those of vehicle-treated cells. Data are presented as mean ± SEM of three samples (***P < 0.001, ****P < 0.0001; ERA, erastin).