TABLE 3.

Univariate and multivariate Cox analysis of signature in CGGA dataset.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-value	HR (95% CI)	p-value
Signature	1.212 (1.174–1.251)	< 0.001	1.182 (1.126–1.242)	< 0.001
Age	1.038 (1.023–1.054)	< 0.001	0.987 (0.969–1.005)	0.155
WHO Grade	3.477 (2.716–4.452)	< 0.001	2.388 (1.739–3.280)	< 0.001
Chemotherapy	1.378 (0.963–1.971)	0.079	0.648 (0.439–0.958)	0.030
Radiotherapy	0.429 (0.296–0.622)	< 0.001	0.383 (0.258–0.570)	< 0.001