TABLE 5.

Univariate and multivariate Cox analysis of signature in GSE16011 dataset.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	p-value	HR (95% CI)	p-value
Signature	1.028 (1.021–1.035)	< 0.001	1.025 (1.016–1.035)	< 0.001
Age	1.042 (1.032–1.053)	< 0.001	1.028 (1.014–1.042)	< 0.001
WHO Grade	2.574 (2.047–3.240)	< 0.001	1.731 (1.256–2.386)	0.001
Chemotherapy	1.571 (1.013–2.436)	0.044	1.420 (0.895-2.254)	0.136
Radiotherapy	0.983 (0.725–1.333)	0.912	0.947 (0.336–2.671)	0.918
KPS	0.980 (0.973–0.986)	< 0.001	0.987 (0.978–0.997)	0.009