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. 2020 Apr 15;105(3):292–298. doi: 10.1136/archdischild-2019-316912

Table 1.

For children included in analysis of outcomes to discharge and outcome at 2 years, characteristics at entry and outcomes to discharge

Included in analysis of outcomes to discharge Included in analysis of outcomes at 2 years
Clamp ≥2 min Clamp ≤20 s Clamp ≥2 min Clamp ≤20 s
n=135 (%) n=134 (%)* n=115 (%) n=102 (%)*
Women’s age (years) mean (SD) 30.5 (6.3) 29.4 (6.7) 30.1 (5.8) 29.8 (6.6)
Gestation at birth (weeks)
 Median (25th, 75th centile) 29 (27.1, 30.7) 29.1 (27.6, 30.4) 29 (27.1, 30.7) 29 (27.0, 30.3)
Two-stage consent pathway 36 (27) 37 (28) 30 (26) 31 (30)
Twin pregnancy 12 (9) 20 (15) 10 (9) 14 (14)
Caesarean delivery 86 (64) 73 (54) 74 (64) 56 (55)
Baby sex
 Male 71 (53) 72 (54) 58 (50) 60 (59)
For live births n=134 n=132 n=114 n=100
Any IVH (grade 1–4) 43 (32) 47 (36) 36 (32) 35 (35)
Severe IVH (grade 3 or 4) 6 (4) 7 (5) 4 (4) 5 (5)
Periventricular leucomalacia 7 (5) 8 (6) 6 (5) 5 (5)
Blood transfusion 63 (47) 68 (52) 53 (46) 58 (58)
Jaundice requiring treatment 123 (92) 120 (91) 105 (92) 89 (89)
Chronic lung disease† 40 (31) 39 (33) 31 (28) 31 (35)
Ventilation 100 (75) 103 (78) 84 (74) 80 (80)
Necrotising enterocolitis 8 (6) 5 (4) 7 (6) 4 (4)
Sepsis‡ 72 (54) 80 (61) 59 (52) 63 (63)
Treatment for patent ductus arteriosis 20 (15) 20 (15) 15 (13) 19 (19)
Duration of hospital stay (nights)§
 Median (25th, 75th centile) 57 (39, 85) 57 (37, 75) 57 (38, 80) 60 (40, 83)
Receiving mother’s breast milk at discharge§¶ 71 (55) 68 (57) 61 (56) 55 (63)

*One woman withdrew (outcome data reported only for death before discharge).

†For babies surviving to 36 weeks postmenstrual age. n=129 clamping ≥2 min, n=120 clamping ≤20 s for all children and n=109, n=88 respectively for children included in analysis at 2 years.

‡Clinical sepsis defined as positive culture and ≥5 days antibiotics or negative culture and ≥5 days antibiotics.

§For babies alive at discharge n=128 clamping ≥2 min, n=120 clamping ≤20 s for all children and n=108, n=88 respectively for children included in analysis at 2 years.

¶Receiving breast milk at discharge not known for three babies in the clamp cord ≥2 min group (two included in analysis at 2 years) and one baby in clamp cord ≤20 s group (not included in analysis at 2 years).

IVH, intraventricular haemorrhage.