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. 2020 Jul 9;11:993. doi: 10.3389/fphar.2020.00993

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Copyright © 2020 Yang, Kong, Shuai, Zhang and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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SSYX administration affects the TLR4/MyD88/CaMKII signaling pathway-related protein expression. (A) Bubble chart of top 9 KEGG signaling pathways linked to SSYX against MetS-induced VA. (B) Representative Western blots and (C) quantitative results of the TLR4, MyD88, CaMKII, and p-CaMKII expression (n = 3 per group). (D) Representative Western blots and (E) quantitative results of the TLR4, MyD88, CaMKII, and p-CaMKII expression in H9C2 cells (n = 3 per group). **P < 0.01 vs. CTL group. ^## P < 0.01 vs. MetS group. For (D, E), *P < 0.05.