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. 2020 Jul 15;10:11671. doi: 10.1038/s41598-020-68426-z

Table 1.

Synthesis of 2,4,5-trisubstituted imidazole derivatives by using NiFe2O4/geopolymer nanocatalyst.

Entry R Product Time (min) Yielda (%) Melting point (°C)
Observed
Melting point (°C)
Reported
1 Benzaldehyde 4a 18 91 277–279 278–28057
2 4-Chlorobenzaldehyde 4b 18 88 262–265 262–26457
3 2-Chlorobenzaldehyde 4c 25 84 196–198 196–19835
4 3-Chlorobenzaldehyde 4d 26 81 296–298 296–29758
5 2,4-Dichlorobenzaldehyde 4e 28 89 174–177 176–17835
6 2,6-Dichlorobenzaldehyde 4f 33 84 236–238 236–23859
7 4-Bromobenzaldehyde 4 g 27 87 265–267 264–26660
8 4-Methoxybenzaldehyde 4 h 30 86 232–234 233–23461
9 3,4,5-Trimethoxybenzaldehyde 4i 33 82 259–261 261–26262
10 2-Methoxybenzaldehyde 4j 35 85 210–212 209–21163
11 4-Methylbenzaldehyde 4 k 33 88 231–233 230–23264
12 4-Hydroxybenzaldehyde 4 l 38 87 261–263 260–26265
13 2-Nitrobenzaldehyde 4 m 30 86 231–233 230–23263
14 4-Nitrobenzaldehyde 4n 26 84 234–236 235–23866
15 4-Fluorobenzaldehyde 4o 32 92 248–250 247–24967
16 Furfural 4p 29 90 237–239 237–23968

aIsolated yield.