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. 2020 Jul 15;11:3548. doi: 10.1038/s41467-020-17178-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a The symptomatic biosignature (2592 transcripts) was applied to symptomatic cCMV-infected infants with samples collected at initial testing (n = 23), 1 year (n = 16), 2 years (n = 12) and 3 years (n = 9) of follow-up. b The asymptomatic cCMV biosignature (3324 transcripts) was also applied to asymptomatic cCMV infants with samples collected at initial testing (n = 15), 1 year (n = 9), 2 years (n = 8), and 3 years (n = 4) of follow-up. Transcripts were organized in a heatmap format where each row represents a transcript and each column represents a patient sample. Red color indicates overexpression and blue color underexpression of a transcript compared with the median expression of healthy controls (yellow).