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. 2020 Jul 9;14:202. doi: 10.3389/fncel.2020.00202

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Copyright © 2020 Zhang, Cao, Qiu, Xu, Chen, Barnes, Tu, Gyabaah, Gharbal, Peng, Cai and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neuronal morphology in the hippocampal CA3–CA1 region detected by hematoxylin and eosin staining. Arrows indicate swollen and heterologous neurons with clear nuclei. Bar: 20 μm. A, room air; AC, intermittent air; IH, intermittent hypoxia; DMSO, IH with DMSO treatment; CCPA, IH with 2-chloro-N (6)-cyclopentyl-adenosine treatment; DPCPX, IH with 8-cyclopentyl-1,3-dipropylxanthine treatment; KO, IH with A1R knockout.