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. 2020 Jul 9;11:763. doi: 10.3389/fphys.2020.00763

FIGURE 1.

FIGURE 1

Improved cardiac function following MI in Vegfr2Y949F/Y949F mice. (A–C) Heart function assessed using echocardiography; (A) ejection fraction, (B) fractional area change (FAC), (C) cardiac output (CO) in Vegfr2Y949F/Y949F mice and WT littermates in baseline condition (n = 8–11 mice/strain), and at 24 h following myocardial infarction (n = 12–13 mice/strain, conducted at three different occasions). (D,E). Heart weights before infarction (D; n = 4 mice/strain) and induced infarct size at 24 h after ligation (E) (n = 12–13 mice/strain) in WT and Vegfr2Y949F/Y949F mice. Data in (A–E) are shown as mean ± SEM. Statistical significance was determined using Mann–Whitney test, *p < 0.05. (F) Survival after large infarct (n = 11–12/strain). Chi-squared test; *p < 0.05. For all panels, n refers to biological replicates.