Table 3.
Mean parasitemia, suppression, and survival time of mice in days (±SD) for extracts at 100 mg/kg.
| Plant (parts used) | Solvent of extraction used | Mean parasitemia | % suppression | Mean survival time in days |
|---|---|---|---|---|
| Terminalia brownii Fresen (leaf) | H2O | 10.8 ± 0.57 | 9.50 ± 3.75 | 8.6 ± 1.67 |
| MEOH | 11.78 ± 0.35 | 11.1 ± 1.9 | 9.2 ± 2.04 | |
| DCM | 11.11 ± 0.48 | 9.88 ± 0.95 | 8.8 ± 1.8 | |
| Erythrina abyssinica Lam. Ex DC (stem bark) | H2O | 10.87 ± 0.67 | 5.44 ± 2.15b | 8.8 ± 1.8 |
| MEOH | 11.54 ± 1.04 | 3.51 ± 1.6d | 9.2 ± 2.04 | |
| DCM | 7.17 ± 0.21 | 36.85 ± 5.07 | 8.6 ± 1.67 | |
| Schkuhria pinnata (Lam.) Kuntze (whole plant) | H2O | 9.32 ± 0.66 | 21.95 ± 7.08b,c | 8.6 ± 1.67 |
| MEOH | 8.18 ± 0.65 | 38.31 ± 6.31d | 9.2 ± 2.04 | |
| DCM | 9.37 ± 0.18 | 23.88 ± 3.10 | 8.8 ± 1.8 | |
| Zanthoxylum chalybeum Engl. (leaf) | H2O | 10.68 ± 0.33 | 10.60 ± 1.78 | 8.6 ± 1.67 |
| MEOH | 10.6 ± 0.55 | 11.37 ± 3.55 | 9.2 ± 2.04 | |
| DCM | 10.3 ± 0.84 | 9.35 ± 1.23 | 8.8 ± 1.8 | |
| Leonotis mollissima Gurke (leaf) | H2O | 7.64 ± 0.68 | 33.21 ± 8.08c | 8.8 ± 1.8 |
| MEOH | 7.63 ± 0.44 | 36.21 ± 5.14d | 9.2 ± 2.04 | |
| DCM | 10.46 ± 0.82 | 7.97 ± 1.63 | 8.6 ± 1.67 | |
| Tithonia diversifolia (Hemsl.) A. Gray (fruit) | H2O | 12.24 ± 0.59 | 7.57 ± 1.08 | 9 ± 2.1 |
| MEOH | 10.76 ± 0.35 | 6.25 ± 2.34 | 9 ± 1.6 | |
| DCM | 11.62 ± 0.61 | 5.69 ± 1.58 | 8.6 ± 1.67 | |
| Tithonia diversifolia (Hemsl.) A. Gray (leaf) | H2O | 10.72 ± 0.53 | 19.044 ± 1.6 | 9 ± 2.1 |
| MEOH | 9.14 ± 0.44 | 20.38 ± 1.86d | 9 ± 1.6 | |
| DCM | 7.26 ± 0.33 | 40.90 ± 4.81 | 8.6 ± 1.67 | |
| Senna didymobotrya (Fresen.) Irwin & Barneby (pod) | H2O | 11.96 ± 0.63 | 9.89 ± 0.85 | 9 ± 2.1 |
| MEOH | 10.64 ± 0.21 | 7.21 ± 4.22 | 9 ± 1.6 | |
| DCM | 11.08 ± 0.47 | 10.00 ± 2.69 | 8.6 ± 1.67 | |
| Senna didymobotrya (Fresen.) Irwin & Barneby (leaf) | H2O | 12.24 ± 0.64 | 7.54 ± 1.72 | 8.6 ± 1.67 |
| MEOH | 12.38 ± 0.45 | 6.48 ± 2.11 | 9.2 ± 2.04 | |
| DCM | 10.52 ± 0.62 | 14.74 ± 2.36 | 8.8 ± 1.8 | |
| Carissa edulis (Forssk.) Vahl (leaf) | H2O | 10.33 ± 0.58 | 10.31 ± 4.8c | 9.4 ± 1.68 |
| MEOH | 9.60 ± 0.45 | 16.66 ± 4.34d | 9.4 ± 1.68 | |
| DCM | 10.56 ± 0.32 | 6.91 ± 3.01 | 9.4 ± 1.68 | |
| Sterculia africana (Lour.) Fiori (stem bark) | H2O | 8.40 ± 0.26 | 39.09 ± 5.32d | 9.4 ± 1.68 |
| MEOH | 7.02 ± 0.68 | 27.06 ± 1.6b,c | 9.4 ± 1.68 | |
| DCM | 10.54 ± 0.32 | 8.50 ± 1.45 | 9.4 ± 1.68 |
a P ≤ 0.05 between the treated and control groups for survival times. bP ≤ 0.05 between water and methanol extracts. cP ≤ 0.05 between water and DCM. dP ≤ 0.05 between methanol and dichloromethane. L: leaves; SB: stem bark; WP: whole plant; F: fruit; P: pods.