Table 3.

Predisposing risk factors for QTc interval prolongation (≥ 500 ms)

Parameters	Univariate analysis		Multivariate analysis
	QTc ≥ 500 ms OR (95% CI)	p value	QTc ≥ 500 ms OR (95% CI)	p value
Baseline QTc prolongation (≥ 440 ms female, ≥ 460 ms male)	3.86 (1.47–10.17)	0.006	7.10 (1.88–26.81)	0.004
Delta QTc > 40 ms (0–3 days)	19.86 (5.93- 66.44)	0.001	30.15 (6.96- 130.55)	0.001
eGFR < 60 ml/min/1.73mq	3.53 (1.32–9.44)	0.012	1.38 (0.41–4.67)	0.600
Non-invasive ventilation	0.43 (0.17–1.08)	0.072
CRP > 50 mg/L	1.40 (0.47–4.18)	0.543
Baseline serum K < 3.8 mg/dL	0.68 (0.22–1.89)	0.417
Baseline serum Na < 138 mg/dL	1.71 ( 0.68–4.30)	0.259

QTc corrected QT interval, eGFR estimated glomerular filtration, CRP C-reactive protein