Table 5. Univariate and Multivariate Cox Proportional Hazards Regression Analysis of Overall Survival for 280 Matched Patients.
Characteristic | Univariable | Multivariable | ||
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Female sex | 1.19 (0.67-2.13) | .50 | NA | NA |
BMI | 1.01 (0.96-1.07) | .70 | NA | NA |
First-line chemotherapy regimen | ||||
FOLFIRINOX | 1 [Reference] | |||
GA | 1.50 (1.00-2.26) | .05 | 1.48 (0.97-2.26) | .07 |
Baseline CA 19-9 level, U/mL | 1.01 (0.99-1.03) | .30 | NA | NA |
Tumor site | ||||
Head or neck | 1 [Reference] | |||
Body or tail | 0.78 (0.39-1.56) | .50 | NA | NA |
No. of chemotherapy cycles | 0.72 (0.52-1.01) | .06 | 0.73 (0.52-1.02) | .06 |
Abbreviations: BMI, body mass index; CA 19-9, cancer antigen 19-9; FOLFIRINOX, fluorouracil, leucovorin, irinotecan, and oxaliplatin; GA, gemcitabine plus nanoparticle albumin-bound paclitaxel; HR, hazard ratio; NA, not applicable.