Table 2. Change in Heinrich Carpenter Quality of Life and Brief Psychiatric Rating Scale Total Scores Between AOM and CC Conditions From Baseline to 12 Months and 24 Monthsa.
| Score | Estimate (95% CI) | |
|---|---|---|
| Change to mo 12 | Change to mo 24 | |
| Heinrich Carpenter quality of life | ||
| Total score | 1.068 (−2.911 to 5.047) | −2.014 (−6.252 to 2.225) |
| Subscale scores | ||
| Interpersonal relationsb | 0.166 (−1.703 to 2.034) | 0.247 (−1.737 to 2.231) |
| Instrumental rolec | 1.079 (−0.575 to 2.732) | −1.095 (−2.856 to 0.666) |
| Intrapsychic foundationsd | 0.137 (−1.285 to 1.559) | −1.015 (−2.535 to 0.504) |
| Common objects and activitiese | −0.055 (−0.459 to 0.349) | −0.104 (−0.535 to 0.328) |
| BPRS scores | ||
| Total score | 0.960 (−1.105 to 3.025) | 0.334 (−1.993 to 2.661) |
| Factor scores | ||
| Anxiety/depressionf | 0.080 (−0.126 to 0.286) | 0.016 (−0.204 to 0.23)7 |
| Anergiag | 0.150 (−0.049 to 0.350) | 0.136 (−0.090 to 0.362) |
| Thought disturbanceh | 0.035 (−0.185 to 0.254) | −0.141 (−0.376 to 0.095) |
| Activationi | −0.021 (−0.129 to 0.087) | −0.017 (−0.138 to 0.105) |
| Hostile suspiciousnessj | 0.062 (−0.128 to 0.252) | −0.014 (−0.219 to 0.191) |
Abbreviations: AOM, aripiprazole once monthly; BPRS, Brief Psychiatric Rating Scale; CC, clinician’s choice.
a
The 3-level model of outcome included treatment, time, treatment by time, and age.
b
Sum of quality of life items 1 to 8.
c
Sum of quality of life items 9 to 12.
d
Sum of quality of life items 13 to 17, 20, and 21.
e
Sum of quality of life items 18 to 19.
f
Mean of BPRS items 1, 2, 5, and 9.
g
Mean of BPRS items 3, 13, and 16.
h
Mean of BPRS items 4, 8, 11, 12. and 15.
i
Mean of BPRS items 6, 7, and 17.
j
Mean of BPRS items 10, 11, and 14.