Table 1.
Characteristics of 273 patients and 352 lesions
| Characteristic | Total | ECA-MRI | HBA-MRI | P-value |
|---|---|---|---|---|
| Patients | 273 | 71 | 202 | |
| Sex, male | 188 (68.9) | 46 (64.8) | 142 (70.3) | 0.456 |
| Age (years)* | 57.3±9.5 | 57.4±9.9 | 57.3±9.4 | 0.950 |
| Etiology | 0.022 | |||
| Hepatitis B | 245 (89.8) | 60 (84.5) | 185 (91.6) | |
| Hepatitis C | 11 (4.0) | 7 (9.9) | 4 (2.0) | |
| Alcohol | 17 (6.2) | 4 (5.6) | 13 (6.4) | |
| Liver cirrhosis | 150 (54.9) | 39 (54.9) | 111 (55.0) | 0.998 |
| Lesions | 352 | 86 | 266 | 0.416 |
| Size (mm)† | 24 (15–34) | 25 (19–32) | 24 (15–35) | 0.416 |
| Size subgroup | 0.307 | |||
| 10–19 mm | 132 (37.5) | 28 (32.6) | 104 (39.1) | |
| ≥20 mm | 220 (62.5) | 58 (67.4) | 162 (60.9) | |
| Categorization according to LI-RADS 2018 | 0.111 | |||
| LR-2 | 30 (8.5) | 7 (8.1) | 23 (8.7) | |
| LR-3 | 14 (4.0) | 7 (8.1) | 7 (2.6) | |
| LR-4 | 59 (16.8) | 9 (10.5) | 50 (18.8) | |
| LR-5 | 188 (53.4) | 48 (55.8) | 140 (52.6) | |
| LR-M | 59 (16.8) | 14 (16.3) | 45 (16.9) | |
| LR-TIV | 2 (0.5) | 1 (1.2) | 1 (0.4) | |
| Categorization according to KLCA-NCC 2018 | 0.135 | |||
| Benign | 31 (8.8) | 11 (12.8) | 20 (7.5) | |
| Indeterminate | 31 (8.8) | 7 (8.1) | 24 (9.0) | |
| Probable HCC | 24 (6.8) | 10 (11.6) | 14 (5.3) | |
| Definite HCC | 207 (58.8) | 44 (51.2) | 163 (61.3) | |
| Targetoid appearance | 59 (16.8) | 14 (16.3) | 45 (16.9) | |
| Final diagnosis | 0.051 | |||
| HCC | 263 (74.7) | 62 (72.1) | 201 (75.6) | |
| Non-HCC malignancy | 37 (10.5) | 9 (10.5) | 28 (10.5) | |
| cHCC-CCA | 23 (6.6) | 5 (5.8) | 18 (6.8) | |
| Intrahepatic cholangiocarcinoma | 9 (2.5) | 3 (3.5) | 6 (2.2) | |
| Hepatoblastoma | 1 (0.3) | 1 (1.2) | 0 (0.0) | |
| Metastasis | 4 (1.1) | 0 (0.0) | 4 (1.5) | |
| Benign lesion | 52 (14.8) | 15 (17.4) | 37 (13.9) | |
| Hemangioma | 14 (4.0) | 4 (4.6) | 10 (3.8) | |
| Focal nodular hyperplasia-like nodule | 8 (2.3) | 6 (7.0) | 2 (0.7) | |
| Regenerative nodule | 17 (4.8) | 3 (3.5) | 14 (5.3) | |
| Dysplastic nodule | 13 (3.7) | 2 (2.3) | 11 (4.1) |
Values are presented as mean±standard deviation, median (interquartile), or number (%).
ECA, extracellular contrast agent; MRI, magnetic resonance imaging; HBA, hepatobiliary agent; LI-RADS, Liver Imaging Reporting and Data System; KLCA, Korean Liver Cancer Association; HCC, hepatocellular carcinoma; cHCC-CCA, combined hepatocellular carcinoma-cholangiocarcinoma.
*
Compared by using the two-sample t test.
†
Compared by using Mann-Whitney U test.