Table 2.
Diagnostic performances of LR-5 of LI-RADS 2018 and definite HCC of KLCA-NCC 2018 for diagnosing HCC on ECA-MRI and HBA-MRI
| LR-5 of LI-RADS 2018 (95% CI) | Definite HCC of KLCA-NCC 2018 (95% CI) | P-value* | |
|---|---|---|---|
| ECA-MRI all (n=86) | |||
| Sensitivity | 75.8 (65.2–86.5) | 69.4 (57.9–80.8) | 0.095 |
| Specificity | 95.8 (87.8–100.0) | 95.8 (87.8–100.0) | >0.999 |
| ECA-MRI 10–19 mm (n=28) | |||
| Sensitivity | 58.8 (35.4–82.2) | 58.8 (35.4–82.2) | >0.999 |
| Specificity | 100.0 (100.0–100.0) | 100.0 (100.0–100.0) | >0.999 |
| ECA-MRI ≥20 mm (n=58) | |||
| Sensitivity | 82.2 (71.1–93.4) | 73.3 (60.4–86.3) | 0.092 |
| Specificity | 92.3 (77.8–100.0) | 92.3 (77.8–100.0) | 0.109 |
| HBA-MRI all (n=266) | |||
| Sensitivity | 68.2 (61.7–74.6) | 79.1 (73.5–84.7) | <0.001 |
| Specificity | 95.4 (90.3–100.0) | 93.9 (88.0–99.7) | 0.314 |
| HBA-MRI 10–19 mm (n=104) | |||
| Sensitivity | 51.6 (39.2–64.1) | 75.8 (65.2–86.5) | <0.001 |
| Specificity | 97.6 (93.0–100.0) | 95.2 (88.8–100.0) | 0.312 |
| HBA-MRI ≥20 mm (n=162) | |||
| Sensitivity | 75.5 (68.4–82.7) | 80.6 (74.0–87.2) | 0.017 |
| Specificity | 91.3 (79.8–100.0) | 91.3 (79.8–100.0) | >0.999 |
LI-RADS, Liver Imaging Reporting and Data System; HCC, hepatocellular carcinoma; KLCA-NCC, Korean Liver Cancer Association-National Cancer Center; ECA, extracellular contrast agent; MRI, magnetic resonance imaging; HBA, hepatobiliary agent; CI, confidence interval.
*
P-values between LR-5 of LI-RADS 2018 and definite HCC of KLCA-NCC 2018 by using the generalized estimating equation method.