Table 3.
Tumor-based analysis
| Breast cancer subtype | Site lesion | 18F-FDG | 68Ga-PSMA-11 | P* |
|---|---|---|---|---|
| LUM A | Local | 6/6 | 2/6 | 0.02 |
| Axillary lymph-node | 4/4 | 1/4 | ||
| mediastinal lymph-node | 3/3 | 1/3 | ||
| distant non-bone metastases | 2/2 | 1/2 | ||
| bone metastases | 4/4 | 2/4 | ||
| LUM B HER2- | Local | 5/5 | 3/5 | 0.05 |
| Axillary lymph-node | 7/7 | 3/7 | ||
| mediastinal lymph-node | 5/5 | 3/5 | ||
| distant non-bone metastases | 4/4 | 2/4 | ||
| bone metastases | 3/3 | 3/3 | ||
| LUM B HER2+ | Local | 8/8 | 4/8 | 0.61 |
| Axillary lymph-node | 5/5 | 3/5 | ||
| mediastinal lymph-node | 6/6 | 5/6 | ||
| distant non-bone metastases | 2/2 | 1/2 | ||
| bone metastases | 5/5 | 5/5 | ||
| HER-2 overexpression | Local | 6/6 | 5/6 | 0.87 |
| Axillary lymph-node | 9/9 | 8/9 | ||
| mediastinal lymph-node | 3/3 | 3/3 | ||
| distant non-bone metastases | 4/4 | 4/4 | ||
| bone metastases | 5/5 | 5/5 | ||
| TPN | Local | 5/5 | 5/5 | 1.0 |
| Axillary lymph-node | 6/6 | 6/6 | ||
| mediastinal lymph-node | 8/8 | 8/8 | ||
| distant non-bone metastases | 3/3 | 3/3 | ||
| bone metastases | 9/9 | 9/9 |
Abbreviations: LUM = molecular subtypes of breast cancer including luminal A and luminal B; HER-2 = human epidermal growth factor receptor 2; TPN = triple negative breast cancer.
*
McNemar test vs. 68Ga-PSMA-11 PET/CT.