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. 2020 Jun 15;12(6):e8632. doi: 10.7759/cureus.8632

Table 1. Baseline characteristics and comparison of results.

Values are given in numbers (percentages).

M, Male; F, Female; Yr, Year; CKD, Chronic kidney disease; TRx, Transplant recipient; AKI, Acute kidney injury; COVID-19, Coronavirus disease 2019; BUN, Blood urea nitrogen; Cr, Creatinine; eGFR, Estimated glomerular filtration rate; IVIG, Intravenous immunoglobulin.

[2], [4], [11-13]

Author /Year Cheng Y, et al. (2020) Chen T, et al. (2020) Gandolfini I, et al. (2020) Wang L, et al. (2020) Zhang H, et al. (2020) Total
Study location   China   China   Italy   China   China  
Number of patients   701   274   2 116 5   1098
M 367 (52%) 171 (62%) 1 (50%) 67 (58%) 4 (80%) 610 (55%)
F  334 (48%)  103 (38%) 1 (50%) 49 (42%) 1 (20%) 488 (45%)
Median age (Yr)   63 62 64 54 45    
Patients with known CKD or TRx 14 (2%) 4 (1%) 2 (100%) 5 (4%) 5 (100%) 30 (3%)
Patients with AKI after COVID-19 infection 36 (5%) 29 (10%) 1 (50%) 0 (0%) 0 (0%)     66 (6%)
On admission: BUN/Cr (mg/dL) (mean)           - 13.72 / 0.86 - / 2.3 With CKD: 89.83±24.03 / 10.62±1.34   Without CKD: 14.65±4.82 / 0.88±0.29 33.27±20.08 / 2.10±1.44          
  Change in BUN/Cr (mg/dL) (mean)           - 23.52 / 0.99 - / 2.8 With CKD: 89.44±25.71 / 10.34±1.85 Without CKD: 14.53±5.80 / 0.82±0.28           -            
Change in eGFR (mL/min) (mean)             -           -           - With CKD: 14.43±7.34 to 22.86±9.37 Without CKD: 129.81±10.33 to 127.96±9.65           -            
Mortality with AKI 34 (94%) 28 (96%) 0 (0%) 0 (0%) 0 (0%) 62 (94%)
Mortality without AKI 79 (12%) 85 (35%) 1 (100%) 7 (6%) 0 (0%) 172 (17%)
Major treatment provided (including mechanical ventilation) Arbidol, interferon, lopinavir and ritonavir, glucocorticoids, antibiotics Antivirals, glucocorticoids, IVIGs, antibiotics, interferon           Hydroxychloroquine, lopinavir + ritonavir, or darunavir + cobicistat, colchicine                   - Antiviral (oseltamivir or arbidol), antibacterial therapy (cefixime), IVIGs, triple immunosuppression with glucocorticoids, mycophenolate mofetil and calcineurin inhibitors