Table 1. Antibodies Binding Selectively to One Eph Receptor.
| target | mAb | tracer | imaging modality | chelators per mAb | antigen | radiolabeling for imaging |
|---|---|---|---|---|---|---|
| EphA2 | 1C1 | 64Cu-DOTA-1C1 | PET | ∼19 | Cai 20078 | |
| EphA2 | 4B3 | 64Cu-NOTA-4B3 | PET | 0.5 | Puttick 20159 | |
| EphA2 | DS-8895a | 111In-CHX-A″-DTPA-DS-8895a; 125I-DS-8895a | SPECT | Burvenich 201610 | ||
| EphA2 | DS-8895a | 89Zr-Df-Bz-NCS-DS-8895a | PET | Burvenich 201610 | ||
| EphA3 | 3A4 | 111In-CHX-A″-DTPA-3A4; 125I-3A4 | SPECT | ephrin-binding domain | Vearing 200511 | |
| EphB4 | hAb47 | 64Cu-DOTA-Lys-hAb47 | PET | ∼3.6 | fibronectin type III domain 2 | Liu 201312 |
| EphB4 | hAb131 | 64Cu-DOTA-Lys-hAb131 | PET | ∼1.9 | fibronectin type III domain 1 | Li 201313 |
| EphB4 | hAb131 | hAb131-F(ab′)2-Cy5.5 | NIRF | fibronectin type III domain 1 | Li 201313 | |
| EphB4 | hAb131 | hAb131-Fab-Cy5.5 | NIRF | fibronectin type III domain 1 | Li 201313 |