Table 3.
Saos-2 Telomere lengths
| End telomere | End telomere loss | Recombined Ends with ITS | ITS Loss | (TTAGGG) n < 500 bp | % Recombinant Subtelomere Molecules % of total analyzed for subtelomere |
Longest Telomere | |
|---|---|---|---|---|---|---|---|
| Chr-parm | Mean Length (kb) ± Std (# telomeres) | (# molecules) | Mean Length (kb) ± Std (# telomeres) | (# molecules) | # molecules (# end, # ITS) | Length (kb) | |
| 1p | 4.8 ± 8.6 (14) | 3 | 1.6 ± 1.8 (23) | 3 | 5 (3,2) | 62 | 30.5 |
| 2p | 4.5 ± 3.5 (31) | 1 | nd | 0 | 1 (1,0) | 0 | 11.0 |
| 3p | 7.5 ± 5.5 (30) | 1 | nd | 0 | 1 (1,0) | 0 | 25.5 |
| 4p | 3.3 ± 2.7 (24) | 2 | nd | 0 | 0 (0,0) | 0 | 9.9 |
| 5p | 5.9 ± 5.6 (14) | 0 | 2.6 ± 1.6 (7) | 0 | 0 (0,0) | 41 | 18.3 |
| 6p | 7.7 ± 7.6 (10) | 1 | 3.1 ± 0 (1) | 0 | 0 (0,0) | 10 | 18.4 |
| 7p | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 8p | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 9p | 4.7 ± 4.2 (17) | 1 | nd | 0 | 0 (0,0) | 0 | 13.6 |
| 10p | 2.1 ± 1.7 (19) | 2 | nd | 0 | 2 (2,0) | 0 | 6.7 |
| 11p | 5.3 ± 5.1 (7) | 0 | 5.0 ± 5.8 (3) | 0 | 0 (0,0) | 30 | 11.8 |
| 12p | 6.5 ± 4.7 (26) | 2 | nd | 0 | 0 (0,0) | 0 | 15 |
| 13p | nr | nr | |||||
| 14p | nr | nr | |||||
| 15p | nr | nr | |||||
| 16p | INP | INP | |||||
| 17p | INP | INP | |||||
| 18p | 3.6 ± 3.0 (31) | 0 | 1.1 ± 0 (1) | 0 | 2 (2,0) | 3 | 13.1 |
| 19p | 4.1 ± 4.0 (30) | 1 | 5.1 ± 3.9 (5) | 0 | 4 (4,0) | 13.2 | |
| 20p | 2.0 ± 1.5 (20) | 1 | nd | 0 | 3 (3,0) | 0 | 4.9 |
| 21p | nr | nr | |||||
| 22p | nr | nr | |||||
| Xp/Yp | nr | nr | |||||
| Chr-qarm | |||||||
| 1q | 4.1 ± 4.6 (25) | 3 | 2.9 ± 2.0 (4) | 0 | 2 (2,0) | 3 | 12.9 |
| 2q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 3q | 0 ± 0 (1) | 1 | 0.9 ± 0.6 (7) | 0 | 3 (0,3) | 88 | 1.8 |
| 4q | 0.7 ± 0.9 (3) | 1 | nd | 0 | 1 (1,0) | 0 | 1.7 |
| 5q | 5.7 ± 3.6 (27) | 0 | 1.5 ± 0 (1) | 0 | 0 (0,0) | 4 | 12.4 |
| 6q | 8.9 ± 10.0 (27) | 2 | 14.5 ± 3.7 (5) | 0 | 2 (2,0) | 16 | 50 |
| 7q | 1.9 ± 1.4 (27) | 0 | 1.3 ± 0 (1) | 0 | 2 (2,0) | 4 | 6.1 |
| 8q | 1.1 ± 0.7 (15) | 1 | 1.4 ± 0.9 (18) | 0 | 3 (3,0) | 55 | 3.4 |
| 9q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 10q | 3.0 ± 3.9 (30) | 0 | 0.7 ± 0.9 (2) | 0 | 2 (1,1) | 15.9 | |
| 11q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 12q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 13q | 6.4 ± 6.2 (30) | 1 | 7.6 ± 6.2 (5) | 0 | 2 (2,0) | 14 | 23.3 |
| 14q | 2.3 ± 2.7 (26) | 1 | nd | 0 | 5 (5,0) | 0 | 6.3 |
| 15q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 16q | 6.8 ± 17.7 (13) | 2 | nd | 0 | 0 (0,0) | 0 | 62.8 |
| 17q | 1.6 ± 1.9 (10) | 2 | 1.7 ± 2.5 (16) | 0 | 4 (0,4) | 62 | 10.1 |
| 18q | 2.6 ± 3.4 (28) | 4 | nd | 0 | 5 (5,0) | 0 | 13.1 |
| 19q | 5.1 ± 5.4 (31) | 12 | 2.6 ± 2.3 (2) | 0 | 1 (1,0) | 20.5 | |
| 20q | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| 21q | 1.3 ± 0.6 (6) | 1 | 1.9 ± 0.7 (22) | 0 | 1 (1,0) | 79 | 3.6 |
| 22q | INP | INP | |||||
| Xq/Yq | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Total | 548 | 46 | 118 | 3 | 52 (42,10) | 19 | |
N/A no data, not enough molecules to measure the telomere length
INP inverted nick pair (INP) sites
nr no reference sequences or significant gaps in the reference sequence
nd Not detected