Figure 6 |.
DNA fragment size distributions measured by a TapeStation. “FU” means fluorescence unit. “Lower” and “Upper” refer to 25 bp and 1500 bp peaks generated by the DNA ladder, respectively. (a) DNA from 10,000 GM12878 cells after crosslinking and sonication. (b) DNA from 2000 nuclei isolated from mouse prefrontal cortex after MNase digestion. (c) Sequencing library after H3K4me3 MOWChIP of 10,000 GM12878 cells and library preparation. (d) Sequencing library after H3K4me3 MOWChIP of 2000 mouse prefrontal cortex nuclei and library preparation.