Table 5.

Candidate drugs targeting hub genes

gene	drug	interaction_types	sources	pmids
CXCR2	PROPOFOL	agonist	GuideToPharmacologyInteractions	–
CXCR2	BENZPIPERYLON	agonist	GuideToPharmacologyInteractions	–
CXCR2	CHEMBL411250	agonist	GuideToPharmacologyInteractions	–
CXCR2	MEPHENTERMINE	agonist	GuideToPharmacologyInteractions	–
CXCR2	REPARIXIN	allosteric modulator|modulator|antagonist	GuideToPharmacologyInteractions|ChemblInteractions|TTD	–
CXCR2	DANIRIXIN	antagonist	GuideToPharmacologyInteractions|ChemblInteractions	–
CXCR2	NAVARIXIN	antagonist	GuideToPharmacologyInteractions|ChemblInteractions|TTD	–
CXCR2	CHEMBL239767	antagonist	GuideToPharmacologyInteractions	–
CXCR2	NAVARIXIN HYDRATE	antagonist	ChemblInteractions	–
CXCR2	ELUBRIXIN	antagonist	ChemblInteractions|TTD	–
CXCR2	Ladarixin	modulator	ChemblInteractions	–
CXCR2	BEVACIZUMAB	–	PharmGKB	–
CXCR2	CYCLOPHOSPHAMIDE	–	PharmGKB	–
CXCR2	ACETYLCYSTEINE	–	NCI	10,716,998
CXCR2	MECHLORETHAMINE HYDROCHLORIDE	–	NCI	12,753,603
CXCR2	VITAMIN E	–	NCI	16,679,868
CXCR2	GENISTEIN	–	NCI	9,712,063
ISG15	IRINOTECAN	inhibitor	MyCancerGenomeClinicalTrial	–
OASL	PEGINTERFERON ALFA-2B	–	PharmGKB	–
OASL	RIBAVIRIN	–	PharmGKB	–
IVL	ETRETINATE	–	NCI	12,445,200|8,381,448
IVL	RETINYL ACETATE	–	NCI	6,189,593
IVL	PERILLYL ALCOHOL	–	NCI	10,769,631
CXCL10	NI-0801	inhibitor	ChemblInteractions	–
CXCL10	METHYLPREDNISOLONE	–	NCI	17,220,550
CXCL10	TESTOSTERONE	–	NCI	9,681,518
CXCL10	REGRAMOSTIM	–	NCI	11,591,765
CXCL10	OXALIPLATIN	–	NCI	16,101,140
CXCL10	ANTIBIOTIC	–	NCI	10,634,213
CXCL10	ZIDOVUDINE	–	NCI	11,141,242
CXCL10	ATROPINE	–	NCI	15,315,164
CXCL10	ELDELUMAB	–	TdgClinicalTrial	–
CXCL10	STAVUDINE	–	NCI	11,141,242
CXCL10	GONADOTROPIN, CHORIONIC	–	NCI	15,590,984
CXCL10	RITONAVIR	–	NCI	11,141,242
CXCL10	ATORVASTATIN	–	NCI	10,559,511