Effect of SCF-RADA16-I
on adhesion and activity of DPSCs. (a) Schematic
diagram of groups: DPSC group: DPSCs were directly inoculated on 24-well
plates; SCF + DPSC group: DPSCs were inoculated on the plates, and
we added SCF to the culture medium; RADA16-I-2D group: RADA16-I was
injected into the insert chamber and completed the self-assembly process,
and then we inoculated DPSCs on the surface of RADA16-I; SCF-RADA16-I-2D
group: we added SCF to the culture medium on the base of group RADA16-I-2D;
and RADA16-I-3D group: RADA16-I in the solution state was mixed with
DPSCs, which were resuspended in sucrose solution, and they were put
into the insert chamber; SCF-RADA16-I-3D group: RADA16-I in the solution
state was mixed with SCF and DPSCs, which were resuspended in sucrose
solutions, and they were injected into the insert chamber. (b, d)
Representative images of two-dimensional cultures and (f, h) the corresponding
statistical analysis . (c, e) The images of three-dimensional cultures
were taken and (g, i) statistically analyzed. F-actin was dyed into
red by phalloidin. The nucleus was dyed into blue by DAPI and dyed
into green by SYTOX Green. (*P < 0.05, **P < 0. 01). Scale bar: 100 μm (b, d) and 200 μm
(c, e).