Table 3.
Analysis to identify conditions related to discrepant trends of eGFRCr and eGFRCysC
| Model 1 | Model 2 | |||
|---|---|---|---|---|
| Variables | OR (95% CI) | P | OR (95% CI) | P |
| Age | 0.92 (0.89–0.95) | < 0.001 | 0.92 (0.89–0.95) | < 0.001 |
| Male | 1.60 (0.61–4.26) | 0.343 | ||
| Age-adjusted CCI | ||||
| Low (≤3) | Reference | |||
| Moderate (4–5) | 1.30 (0.53–3.12) | 0.563 | ||
| High (6–7) | 1.66 (0.28–7.28) | 0.541 | ||
| Very high (≥8) | 2.48 (0.02–30.54) | 0.608 | ||
| Body surface area | 2.01 (0.18–20.83) | 0.562 | ||
| Diastolic blood pressure | 1.01 (0.98–1.04) | 0.579 | ||
| Hemoglobin | 0.90 (0.71–1.13) | 0.350 | ||
| Blood urea nitrogen | 0.99 (0.92–1.05) | 0.661 | ||
| Uric acid | 0.91 (0.74–1.12) | 0.379 | ||
| Phosphorus | 0.83 (0.42–1.62) | 0.590 | ||
| Total bilirubin | 2.00 (0.52–7.35) | 0.307 | ||
| uPCR (g/g) | ||||
| < 0.3 | Reference | Reference | ||
| 0.3–0.9 | 1.69 (0.49–5.26) | 0.392 | 1.53 (0.68–3.45) | 0.305 |
| 1.0–3.0 | 4.54 (0.95–21.44) | 0.058 | 3.32 (1.43–7.84) | 0.006 |
| ≥ 3.0 | 17.87 (3.14–102.19) | 0.001 | 12.38 (4.07–37.39) | < 0.001 |
| uACR (mg/g) | ||||
| < 30 | Reference | |||
| 30–299 | 2.53 (0.74–10.73) | 0.145 | ||
| ≥ 300 | 1.55 (0.27–10.19) | 0.630 | ||
| eGFRCrCysC | 1.07 (1.04–1.10) | < 0.001 | 1.07 (1.05–1.09) | < 0.001 |
Model 1: Adjusted for age, sex, eGFRCrCys and the variables which had P value less than 0.1 in univariate analysis
Model 2: Model 1 with backward elimination method
CCI Charlson comorbidities index; OR Odds ratio; CI Confidence interval; uPCR Urine protein/creatinine ratio; uACR Urine albumin/creatinine ratio; eGFR, estimated glomerular filtration rate; Cr Creatinine; CysC Cystatin C