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. Author manuscript; available in PMC: 2020 Jul 16.
Published in final edited form as: J Vasc Interv Radiol. 2019 Jun 13;30(9):1480–1486.e2. doi: 10.1016/j.jvir.2019.03.004

Figure 1.

Figure 1.

Schematic illustration of a SiNc-based photo-theranostic nanoprobe (SiNc-TN) designed for tumor localization and subsequent combinatorial phototherapy. The nanoprobe consists of SiNc photoactive molecules encapsulated in the hydrophobic center of PEG–PCL polymeric nanoparticles. SiNc-TNs accumulate in tumors and can be detected via NIR fluorescence imaging. When irradiated with NIR laser light, SiNc-TNs transform the absorbed light energy into toxic ROS and heat to eradicate tumor tissue.