Table 2.
Performances of habitation to ASR versus other CRS-R MCS items
| Pr (%) | AUC [95% CI] | Sen, % [95% CI] | Sp, % [95% CI] | PPV, % [95% CI] | NPV, % [95% CI] | PLR [95% CI] | NLR [95% CI] | Acc, % [95% CI] | |
|---|---|---|---|---|---|---|---|---|---|
| Habituation of auditory startle reflex | |||||||||
| Exhaustible | 55 | 0.70 [0.60–0.79] | 75 [60–86] | 65 [49–78] | 68 [54– 80] | 72 [56–85] | 2.12 [1.40–3.21] | 0.39 [0.23–0.66] | 70 [60–79] |
| Auditory | |||||||||
| Reproducible (3) | 9 | 0.59 [0.54–0.66] | 19 [9–33] | – | – | 55 [44–66] | – | 0.81 [0.71–0.93] | 59 [49–69] |
| Systematic (4) | 5 | 0.55 [0.51–0.6] | 10 [3–23] | – | – | 53 [42–63] | – | 0.90 [0.81–0.99] | 55 [45–65] |
| Visual | |||||||||
| Fixation (2) | 6 | 0.56 [0.52–0.61] | 12 [5–25] | – | – | 53 [43–64] | – | 0.88 [0.79–0.97] | 56 [46–66] |
| Pursuit (3) | 25 | 0.75 [0.68–0.82] | 50 [35–65] | – | – | 67 [55–77] | – | 0.50 [0.38–0.66] | 75 [65–83] |
| Localization (4) | 2 | 0.52 [0.5–0.55] | 4 [1–14] | – | – | 51 [41–62] | – | 0.96 [0.90–1.02] | 52 [42–62] |
| Recognition (5) | 5 | 0.55 [0.51–0.59] | 10 [3–23] | – | – | 53 [42–63] | – | 0.90 [0.81–0.99] | 55 [45–65] |
| Motor subscale | |||||||||
| Localization (3) | 7 | 0.57 [0.53–0.62] | 15 [6–28] | – | – | 54 [43–65] | – | 0.85 [0.76–0.96] | 57 [47–67] |
| Manipulation (4) | 2 | 0.52 [0.5–0.55] | 4 [1–14] | – | – | 51 [41–62] | – | 0.96 [0.90–1.02] | 52 [42–62] |
| Automatic (5) | 16 | 0.66 [0.59–0.72] | 31 [19–46] | – | – | 59 [48–70] | – | 0.69 [0.57–0.83] | 66 [55–75] |
| Oromotor and verbal subscale | |||||||||
| Verbalization (3) | 1 | 0.51 [0.5–0.53] | 2 [0–11] | – | – | 51 [40–61] | – | 0.98 [0.94–1.02] | 51 [41–61] |
| Communication subscale | |||||||||
| Intentional (1) | 8 | 0.58 [0.53–0.64] | 17 [7–30] | – | – | 55 [44–65] | – | 0.83 [0.73–0.95] | 58 [48–68] |
Acc = accuracy; AUC = area under the ROC curve; NLR = negative likelihood ratio; NPV = negative predictive value; PLR = positive likelihood ratio; PPV = positive predictive value; Pr = prevalence; Sen = sensitivity; Sp = specificity. CRS-R MCS item scores are given in parentheses.